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KMID : 0604520160420040343
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Journal of the Society of Cosmetic Scientists of Korea
2016 Volume.42 No. 4 p.343 ~ p.349
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Skin Hydration Effect of Jeju Lava Sea Water
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Lee Sung-Hoon
Bae Il-Hong
Min Dae-Jin
Kim Hyoung-June
Park Nok-Hyun
Choi Ji-Yei
Shin Jin-Seob
Kim Eun-Joo
Lee Hae-Kwang
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Abstract
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Many minerals and nutrient salts are abundant in Jeju lava sea water. The objective of this study was to evaluate the skin hydration effects of Jeju lava sea water. The skin barrier serves as a protective barrier that prevents the loss of moisture. The water holding capacity and water transport of the epidermis have been proposed to be important determinants of skin hydration. Jeju lava sea water increased the mRNA expression of filaggrin and caspase-14 which is related to natural moisturizing factor (NMF) formation. Aquaporins 3 (AQP3) are proteins that facilitate the transport of water across cell membranes. Jeju lava sea water increased the mRNA expression and protein expression of AQP3. We employed a skin equivalent model to assess the efficacy of Jeju lava sea water. In a skin equivalent model, Jeju lava sea water increased the CD44 (hyaluronic acid receptor) which is related to skin hydration. From these results, we found out Jeju lava sea water maybe help to skin hydration.
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KEYWORD
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Jeju lava water, skin hydration, NMF, AQP3, skin equivalent
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